NK314
NK314 is a synthetic benzo[c]phenanthridine alkaloid with potent antitumor activity, functioning as a topoisomerase II poison that induces rapid, proteinase K-independent DNA cleavage. Its mechanism and efficacy have been studied in vitro and in vivo, supporting its application in cancer research, particularly in investigating DNA damage and chemotherapeutic strategies.
Product Specifications
CAS Number
208237-49-4
Field of Research
Molecular Biology
Smiles
[Cl-].COc1ccc2c (c3CCC[n+]3c3c4cc5OCOc5cc4ccc23) c1O
Molecular Formula
C22H20ClNO4
Molecular Weight
397.85
Storage Conditions
-20°C
Notes
For research use only.
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