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APcK110

APcK110 is a novel, potent Kit inhibitor that suppresses proliferation in mastocytosis and AML cell lines by dose-dependently inhibiting Kit phosphorylation and downstream Stat3, Stat5, and Akt signaling. Its superior potency compared to imatinib and dasatinib in models like OCI/AML3 supports its research application in acute myeloid leukemia (AML) therapeutics.

Product Specifications

CAS Number

1001083-74-4

Field of Research

Signal Transduction

Smiles

FC1=CC=C (C=2C=3C (=NC (=CC3) C4=CC (OC) =CC (OC) =C4) NN2) C=C1

Molecular Formula

C20H16FN3O2

Molecular Weight

349.36

Storage Conditions

-20°C

Notes

For research use only.

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