Atiprimod (free base)
Atiprimod is an orally active azaspirane that inhibits STAT3 phosphorylation, disrupting IL-6 and VEGF signaling. This action downregulates anti-apoptotic proteins like Bcl-2, leading to cell cycle arrest and apoptosis in various cancer models, as demonstrated in both in vitro and in vivo studies.
Product Specifications
CAS Number
123018-47-3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (CCN (CC) CC) N1CC2 (CCC (CCC) (CCC) CC2) CC1
Molecular Formula
C22H44N2
Molecular Weight
336.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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