Daratumumab Biosimilar - Research Grade
Product Specifications
Background
Daratumumab biosimilar is an immunoglobulin G1 kappa (IgG1κ) human monoclonal antibody against CD38 antigen, produced in a mammalian cell line (Chinese Hamster Ovary [CHO]) using recombinant DNA technology. The molecular weight of daratumumab is approximately 148 kDa.
Specifications
Detects human CD38. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Daratumumab.
Product Name Alternative
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 , ADPRC 1, cADPr hydrolase 1
UniProt
P56528
Host
Humanized
Species Reactivity
Human
Target
CD38
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control
https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/
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