EGFR-IN-2
EGFR-IN-2 is an orally bioavailable, mutation-selective EGFR inhibitor designed for NSCLC research. It potently targets T790M resistance mutants (IC50 27-33 nM) while sparing wild-type EGFR (IC50 218 nM) . This profile supports its investigation in preclinical models for overcoming tyrosine kinase inhibitor resistance.
Product Specifications
CAS Number
1643497-70-4
Product Name Alternative
EGFRIN2, EGFR, EGFR IN 2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.52% (May vary between batches)
Smiles
[C@@H] (CC) (C) N1N=C (C=2C1=CC (NC3=NC (=NC=C3) C4=CN (S (=O) (=O) C5CC5) N=C4) =NC2) N6CC (C (C) (C) O) C6
Molecular Formula
C26H33N9O3S
Molecular Weight
551.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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