Gefitinib N-oxide
Gefitinib is a potent and selective EGFR tyrosine kinase inhibitor, with an IC50 range of 2-37 nM. Its N-oxide derivative is a key metabolite studied in cancer research, utilized in both in vitro cell-based assays and in vivo models to investigate EGFR-driven oncogenesis and drug metabolism.
Product Specifications
CAS Number
847949-51-3
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C=1C2=C (C=C (OC) C (OCCCN3 (=O) CCOCC3) =C2) N=CN1) C4=CC (Cl) =C (F) C=C4
Molecular Formula
C22H24ClFN4O4
Molecular Weight
462.9
Storage Conditions
-20°C
Notes
For research use only.
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