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LY3154207

LY3154207 is a potent, orally bioavailable, and highly selective positive allosteric modulator (PAM) of the human dopamine D1 receptor, exhibiting an EC50 of 3 nM with negligible intrinsic agonist activity. This compound is a valuable research tool for investigating D1 receptor function in neurological disorders, supporting both in vitro binding assays and in vivo behavioral studies.

Product Specifications

CAS Number

1638667-79-4

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C[C@@H]1N ([C@@H] (CO) Cc2c (CCC (C) (C) O) cccc12) C (=O) Cc1c (Cl) cccc1Cl

Molecular Formula

C24H29Cl2NO3

Molecular Weight

450.4

Storage Conditions

-20°C

Notes

For research use only.

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