M8891
M8891 is a potent, orally bioavailable, and brain-penetrant inhibitor of Methionine Aminopeptidase-2 (MetAP-2) with a Ki of 4.33 nM. This small molecule exhibits antiangiogenic and antitumor activity by inhibiting the growth of both endothelial and tumor cells in vitro, supporting research in oncology and angiogenesis.
Product Specifications
CAS Number
1464842-09-8
Field of Research
Metabolism Research
Smiles
O[C@@]1 (CCN (C1=O) c1ccc2[nH]ccc2c1) C (=O) NCc1cc (F) cc (F) c1
Molecular Formula
C20H17F2N3O3
Molecular Weight
385.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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