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PIM1-IN-1

PIM1-IN-1 is a highly selective small molecule inhibitor of PIM kinases, demonstrating potent activity against PIM1 (IC50 = 7 nM) and PIM3, with significantly less effect on PIM2. It exhibits antiproliferative effects in vitro and has shown efficacy in reducing tumor growth in xenograft models, supporting its use in cancer research.

Product Specifications

CAS Number

1417630-95-5

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

98.59% (May vary between batches)

Smiles

N=1N=C2C=3OCCN (C3C=NN2C1C4=NC=5C (=CC=CC5NCC6CCNCC6) C=C4) CCOC

Molecular Formula

C25H30N8O2

Molecular Weight

474.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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