NSC745885
NSC745885 is a small molecule that selectively induces proteasomal degradation of EZH2, demonstrating potent anti-tumor activity in vitro against various cancer cell lines, including bladder and oral squamous cell carcinoma, while sparing normal cells. Its mechanism supports research in oncology, particularly for studying epigenetic-targeted therapies in preclinical models.
Product Specifications
CAS Number
4219-52-7
Product Name Alternative
EZH2, NSC 745885, NSC745885, NSC-745885
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
O=C1C=2C=CC=CC2C (=O) C=3C4=NSN=C4C=CC13
Molecular Formula
C14H6N2O2S
Molecular Weight
266.27
Storage Conditions
-20°C
Notes
For research use only.
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