Mivebresib-alkyne
Mivebresib-alkyne (Compound 25), a Mivebresib derivative, can be used for BRD4 targeted PROTAC synthesis through click reaction[1].
Product Specifications
CAS Number
2409674-37-7
UNSPSC
12352005
Target
Epigenetic Reader Domain; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mivebresib-alkyne.html
Smiles
O=C(C(N1)=CC(C(C2=CC(NS(=O)(CC)=O)=CC=C2OC3=CC=C(F)C=C3F)=CN4C)=C1C4=O)NCC#C
Molecular Formula
C26H22F2N4O5S
Molecular Weight
540.54
References & Citations
[1]Zhang J, et al. Development of small-molecule BRD4 degraders based on pyrrolopyridone derivative. Bioorg Chem. 2020 Jun;99:103817.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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