EN460
EN460 is a selective small molecule inhibitor of Endoplasmic Reticulum Oxidase 1 (ERO1α/ERO1L) . It effectively blocks ERO1L-mediated functions, including gene silencing and cell migration, and inhibits pancreatic ductal adenocarcinoma (PDAC) invasion in research models. This compound is a valuable tool for studying ER stress, tumor metastasis, and ERO1α biology in both cellular and in vivo contexts.
Product Specifications
CAS Number
496807-64-8
Product Name Alternative
EN460, EN-460, EN 460
Purity
99.23% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:8 mg/mL (17.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.17 mM)
Smiles
O=C (O) C1=CC (=CC=C1Cl) N2N=C (C (=CC=3OC (=CC3) C=4C=CC=CC4) C2=O) C (F) (F) F
Molecular Formula
C22H12ClF3N2O4
Molecular Weight
460.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Solute Carrier Family 18, Member 1 (SLC18A1) Antibody
CUG-BP1 Recombinant Antibody, AbBy Fluor™ 594 Conjugated
