CUG-BP1 Recombinant Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB.

Synonyms

BRUNOL2; celf1; CUGBP; CUGBP1; EDEN BP; hNab50; NAB50; NAPOR.

Gene ID

10658

Swiss Prot

Q92879

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CUG-BP1

Clonality

Recombinant

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human CELF 1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-62319R-BF594

Gene ID URL