Phorbol 12,13-dibutyrate
Phorbol 12,13-dibutyrate is a potent protein kinase C (PKC) activator used in cardiovascular research. It demonstrates concentration-dependent inhibition of α1-adrenoceptor-mediated positive inotropic effects, as studied in isolated rabbit vascular smooth muscle preparations. This small molecule is a valuable tool for investigating PKC signaling pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
37558-16-0
Product Name Alternative
PDBu, PKC, Phorbol, Phorbol 12,13 dibutyrate, Phorbol 12,13dibutyrate, Phorbol 12,13-dibutyrate, Phorbol dibutyrate
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
99.32% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.93 mM) ; DMSO:242.5 mg/mL (480.57 mM)
Smiles
[H][C@]12[C@]3 ([H]) C=C (CO) C[C@]4 (O) C (=O) C (C) =C[C@@]4 ([H]) [C@@]3 (O) [C@H] (C) [C@@H] (OC (=O) CCC) [C@@]1 (OC (=O) CCC) C2 (C) C
Molecular Formula
C28H40O8
Molecular Weight
504.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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