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Tetrahydrocortisol

Tetrahydrocortisol is a reduced metabolite of cortisol and a neurosteroid derivative. It functions as a GABAA receptor antagonist and has demonstrated intraocular pressure-lowering effects, making it relevant for neuropharmacology and glaucoma research in experimental models.

Product Specifications

CAS Number

53-02-1

Product Name Alternative

Human Endogenous Metabolite, Tetrahydrocortisol, Tetrahydrohydrocortisone

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

97.01% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.73 mM) ; DMSO:40 mg/mL (109.14 mM)

Smiles

C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@H] (O) CC4) [H]) ([C@@H] (O) C1) [H]) [H]) (CC[C@@]2 (C (CO) =O) O) [H]

Molecular Formula

C21H34O5

Molecular Weight

366.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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