What is the catalog number for PDE6A Antibody?

The catalog number for PDE6A Antibody is 56-928.

What sizes are available for PDE6A Antibody?

PDE6A Antibody is available in the following size(s): 400 µL.

Is PDE6A Antibody in stock?

PDE6A Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PDE6A Antibody

Product Specifications

Background

This gene encodes the cyclic-GMP (cGMP) -specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

NCBI Gene ID

5145

Swiss Prot

P16499

Accession Number

P16499

Host

Rabbit

Reactivity

Human

Immunogen

This PDE6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the Central region of human PDE6A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

100 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PDE6A

NCBI Official Name

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

NCBI Organism

Homo sapiens

Background Reference 01

Clark, G.R., et al. Ophthalmology 117 (11) :2169-2177 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Perlis, R.H., et al. Biol. Psychiatry 67 (11) :1110-1113 (2010)

Background Reference 04

Bazhin, A.V., et al. Cell. Mol. Life Sci. 67 (5) :817-828 (2010)

Other Product Names

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, GMP-PDE alpha, PDE V-B1, PDE6A, PDEA

Tested Applications

Protein ID

215274230

Physical Properties

Liquid

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

I1360 96 Tests

UPF0464 protein C15orf44 (C15orf44) Human ELISA Kit

View Details

SC332524 10 µg

KRTAP29-1 (NM_001257309) Human Untagged Clone

View Details

NBP1-43363PEATT594 0.1 mL

Rat Monoclonal M-CSF R/CD115 Antibody (AFS98) [PE/Atto594]

View Details

MBS8116412-01 0.3 mg

Mouse CXCL16 HEK293 Overexpression Lysate

View Details

MBS8116412-02 5x 0.3 mg

Mouse CXCL16 HEK293 Overexpression Lysate

View Details

abx028746-01 80 µL

BAG Family Molecular Chaperone Regulator 4 (BAG4) Antibody

View Details