TC-N 1752
TC-N 1752 is a potent, orally bioavailable small molecule inhibitor of the voltage-gated sodium channel Nav1.7 (IC50 = 0.17 μM) . It demonstrates analgesic efficacy in preclinical models, making it a valuable research tool for investigating neuropathic pain mechanisms in both in vitro and in vivo studies.
Product Specifications
CAS Number
1211866-85-1
Product Name Alternative
Nav1.7 channel, SodiumChannel, Sodium Channel, TC N 1752, TCN 1752, TC-N 1752, TC-N1752, TC-N-1752
Field of Research
Pharmacology & Drug Discovery
Purity
97.87% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (217.8 mM)
Smiles
CC (=O) Nc1cccc (Nc2ncnc (n2) N2CCC (CC2) OCc2ccc (OC (F) (F) F) cc2) c1C
Molecular Formula
C25H27F3N6O3
Molecular Weight
516.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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