KHK-IN-2
KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor, exhibiting an IC50 of 0.45 μM. This small molecule is a valuable research tool for investigating fructose metabolism in models of metabolic diseases, including non-alcoholic fatty liver disease (NAFLD), in both cellular and animal studies.
Product Specifications
CAS Number
2135304-43-5
Product Name Alternative
Ketohexokinase (KHK), KHKIN2, KHK-IN-2, KHK, KHK IN 2
Field of Research
Metabolism Research
Purity
98.91% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.43 mM) ; DMSO:200 mg/mL (537.14 mM)
Smiles
C[C@]1 (O) CCN (C1) c1nc (cc (c1C#N) C (F) (F) F) N1C[C@H] (O) [C@@H] (O) C1
Molecular Formula
C16H19F3N4O3
Molecular Weight
372.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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