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(S,R,S)-AHPC-C2-NH2 (dihydrochloride)

Product Specifications

UNSPSC Description

(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-c2-nh2-dihydrochloride.html

Purity

98.63

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCN)=O.Cl.Cl

Molecular Weight

574.56

References & Citations

[1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-136163/S-R-S-AHPC-C2-NH2-dihydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-136163/S-R-S-AHPC-C2-NH2-dihydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2341796-73-2

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