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CM-414

CM-414 is a dual HDAC and PDE5 inhibitor with potent activity against key isoforms. In Alzheimer's disease models, it reduces Aβ and pTau, enhances synaptic gene expression, and rescues cognitive and neuronal deficits, supporting its use in neurodegenerative disease research.

Product Specifications

CAS Number

1624792-70-6

Field of Research

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Smiles

C (CC) C=1C2=C (C (=O) N=C (N2) C3=C (OCC) C=CC (C[C@H]4C[C@@H] (C (NO) =O) C4) =C3) N (C) N1

Molecular Formula

C23H29N5O4

Molecular Weight

439.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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