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Methotrexate monohydrate

Methotrexate monohydrate is a potent inhibitor of dihydrofolate reductase (DHFR), leading to suppressed T cell activation, reduced cytokine production, and enhanced T cell apoptosis. This small molecule is widely used in immunology and oncology research, with established applications in both in vitro cellular assays and in vivo models of autoimmune disease and inflammation.

Product Specifications

CAS Number

6745-93-3

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Smiles

NC=1C2=C (N=CC (CN (C) C3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =N2) N=C (N) N1.O

Molecular Formula

C20H24N8O6

Molecular Weight

472.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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