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MS453

MS453 is a potent and selective small-molecule inhibitor of the histone methyltransferase SETD8, exhibiting an IC50 of 804 nM. It serves as a valuable chemical probe for epigenetic research, enabling the study of histone H4 lysine 20 monomethylation (H4K20me1) in cellular and biochemical assays.

Product Specifications

CAS Number

2059892-29-2

Field of Research

Epigenetics & Chromatin

Smiles

N (CCCNC (C=C) =O) C=1C2=C (N=C (N1) N3CCCC3) C=C (OC) C (OC) =C2

Molecular Formula

C20H27N5O3

Molecular Weight

385.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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