BIBP3226
BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect[1][2].
Product Specifications
CAS Number
159013-54-4
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bibp3226.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](CCC/N=C(N)\N)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)=O)NCC3=CC=C(C=C3)O
Molecular Formula
C27H31N5O3
Molecular Weight
473.57
References & Citations
[1]Mollereau C, et al. Agonist and antagonist activities on human NPFF (2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133 (1) :1-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y1 receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Purified Anti-Human CD184 Antibody[12G5]](https://cdn.genprice.uk/products/763/68dd14c3061270361e7d6f57/imageurl/e-ab-f1157a.webp)