Ganoderenic acid B
Ganoderenic acid B is a natural lanostane triterpenoid isolated from Ganoderma lucidum that acts as an ABCB1 transporter inhibitor. It reverses multidrug resistance in vitro by enhancing the cytotoxicity of chemotherapeutic agents in ABCB1-overexpressing cancer cells.
Product Specifications
CAS Number
100665-41-6
Product Name Alternative
ABCB1, Ganoderenic acid B, Pgp
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.41 mM) ; DMSO:90 mg/mL (174.88 mM)
Smiles
CC (CC (=O) \C=C (/C) [C@@H]1CC (=O) [C@@]2 (C) C3=C (C (=O) C[C@]12C) [C@@]1 (C) CC[C@H] (O) C (C) (C) C1C[C@@H]3O) C (O) =O
Molecular Formula
C30H42O7
Molecular Weight
514.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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