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O-11

O-11 is a myristic acid analog where oxygen replaces the methylene at carbon 11. It potently and selectively kills Trypanosoma brucei (LD50 <1 μM) by inhibiting myristate incorporation into the VSG GPI anchor, disrupting immune evasion. It shows minimal anti-fungal activity but minor inhibition of HIV-1 replication in T-cells.

Product Specifications

CAS Number

119290-12-9

Field of Research

Infectious Disease & Virology

Smiles

C (CCCCOCCC) CCCCC (O) =O

Molecular Formula

C13H26O3

Molecular Weight

230.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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