5-Hydroxymethyl-2'-deoxycytidine
5-Hydroxymethyl-2'-deoxycytidine (5-hmdC) is an oxidative DNA lesion derived from 5-methylcytosine, associated with genomic instability and PARP1-mediated replication fork stress. This product is used in epigenetics and DNA damage research to study its roles in cellular toxicity, chromosomal aberrations, and related in vitro and in vivo models.
Product Specifications
CAS Number
7226-77-9
Product Name Alternative
5-Hydroxymethyl-2'-deoxycytidine, 5Hydroxymethyl2'deoxycytidine, 5hmdC, 5 Hydroxymethyl 2' deoxycytidine, PARP1
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
99.80% (May vary between batches)
Solubility
DMSO:45 mg/mL (174.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.77 mM)
Smiles
Nc1nc (=O) n (cc1CO) [C@H]1C[C@H] (O) [C@@H] (CO) O1
Molecular Formula
C10H15N3O5
Molecular Weight
257.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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