PI3Kγ inhibitor 5
PI3Kγ inhibitor 5 is a highly potent and selective small molecule targeting phosphoinositide 3-kinase gamma, with an IC50 of 34 nM. It is a valuable research tool for studying PI3Kγ signaling in inflammation and immuno-oncology, applicable in both cellular assays and in vivo disease models.
Product Specifications
CAS Number
2566569-31-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C[C@@H] (C1CC1) N1Cc2cc (cc (OC (F) F) c2C1=O) -c1ccn2nc (N) c (C (=O) N[C@H]3CC[C@@] (C) (O) CC3) c2n1 |wU:33.36,1.0, wD:30.32,33.37, (10.69, -4.01, ;9.15, -4.01, ;8.38, -5.34, ;8.38, -6.88, ;7.05, -6.11, ;8.38, -2.67, ;6.85, -2.51, ;6.53, -1.01, ;5.2, -.24, ;5.2,1.3, ;6.53,2.07, ;7.87,1.3, ;9.2,2.07, ;9.2,3.61, ;7.87,4.38, ;10.53,4.38, ;7.87, -.24, ;9.01, -1.27, ;10.52, -.95, ;3.86,2.07, ;3.86,3.61, ;2.53,4.38, ;1.2,3.61, ; -.27,4.09, ; -1.17,2.84, ; -2.71,2.84, ; -.27,1.6, ; -.74, .13, ; .29, -1.01, ; -2.25, -.19, ; -2.73, -1.65, ; -4.23, -1.97, ; -4.71, -3.44, ; -3.68, -4.58, ; -3.1, -6.01, ; -4.98, -5.4, ; -2.17, -4.26, ; -1.7, -2.8, ;1.2,2.07, ;2.53,1.3, ) |
Molecular Formula
C28H32F2N6O4
Molecular Weight
554.599
Storage Conditions
-20°C
Notes
For research use only.
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