AChE/PDE4-IN-1

AChE/PDE4-IN-1 (12c) is a potent dual inhibitor of acetylcholinesterase (IC50=0.28 μM) and PDE4D (IC50=1.88 μM) . It shows promise in Alzheimer's disease research for mitigating neuroinflammation and cognitive deficits, as evidenced by in vitro enzymatic assays and in vivo models.