What is the catalog number for TCL1?

The catalog number for TCL1 is T206909.

What sizes are available for TCL1?

TCL1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TCL1 come in?

TCL1 is available in 2 different pack sizes.

TCL1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TCL1?

TCL1 is manufactured by Molfinity.

What is the estimated delivery time for TCL1?

Estimated delivery time for TCL1 is approximately 10 business day(s), depending on your location.

TCL1

Product Specifications

CAS Number

875165-39-2

Target

Proteasome

Related Pathways

Proteases/Proteasome, Ubiquitination

Bioactivity

TCL1 acts as a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit within the 19S regulatory particle (19S RP) of the proteasome, with an IC50 value around 26 μM. It disrupts the recognition and transport of ubiquitinated proteins by Rpn-13, thus inhibiting proteasomal degradation and affecting intracellular protein metabolism balance. TCL1 holds potential for research in hematologic malignancies.