OTS964
OTS964 is a potent, orally bioavailable small molecule that selectively inhibits TOPK (IC50 = 28 nM) and binds CDK11B with high affinity (Kd = 40 nM) . It is a valuable research tool for investigating oncology pathways and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1338542-14-5
Field of Research
Cell Biology, Signal Transduction
Smiles
OC=1C (=C2C3=C (C (=O) NC2=C (C) C1) SC=C3) C4=CC=C ([C@H] (CN (C) C) C) C=C4
Molecular Formula
C23H24N2O2S
Molecular Weight
392.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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