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SMO-IN-1

SMO-IN-1 (Compound 15) is a bioavailable, orally active inhibitor of the Smoothened (SMO) receptor with an EC50 of 89 nM against Sonic Hedgehog (Shh) signaling. This tool compound is used in both in vitro and in vivo studies to investigate the Hedgehog pathway's role in development and disease.

Product Specifications

CAS Number

1126365-66-9

Field of Research

Stem Cell & Developmental Biology

Smiles

N (C (=O) C1=CC=C (OCC2=CC=CC=N2) C=C1) C=3C=C (C=CC3C) C=4N=CN (C) C4

Molecular Formula

C24H22N4O2

Molecular Weight

398.46

Storage Conditions

-20°C

Notes

For research use only.

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