What is the catalog number for NOTCH2 Antibody?

The catalog number for NOTCH2 Antibody is OACD06057-100UL.

What sizes are available for NOTCH2 Antibody?

NOTCH2 Antibody is available in the following size(s): 100 µL.

Is NOTCH2 Antibody in stock?

NOTCH2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

NOTCH2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Notch receptor 2

Gene Aliases

AGS2; HJCYS; hN2; neurogenic locus notch homolog protein 2; notch 2; Notch homolog 2.

Gene ID

4853

Accession Number

NP_001186930.1

Reactivity

Human|Porcine|Rat

Immunogen

Recombinant NOTCH2 (Ala2251 - Asn2466) expressed in E.coli

Target

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity) . Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation (PubMed:29149593) . Positively regulates self-renewal of liver cancer cells (PubMed:25985737) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Specificity

The antibody is a rabbit polyclonal antibody raised against NOTCH2. It has been selected for its ability to recognize NOTCH2 in immunohistochemical staining and western blotting.