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LPM4870108

LPM4870108 is a potent and orally bioavailable pan-Trk inhibitor with high selectivity for Trk over ALK. It demonstrates nanomolar potency against wild-type and mutant Trk isoforms (TrkA, TrkC, TrkAG595R, TrkAG667C) . This profile supports its research use in investigating Trk-driven oncology, with studies showing antitumor efficacy in relevant preclinical models.

Product Specifications

Field of Research

Signal Transduction

Molecular Formula

C20H19FN6O3

Molecular Weight

410.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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