AMG8788
AMG8788 is a potent, selective, and orally bioavailable antagonist of the TRPM8 ion channel, exhibiting an IC50 of 63.2 nM. This compound is a valuable research tool for investigating TRPM8's role in vivo and in vitro, particularly in areas such as cold sensation, migraine, and urological disorders.
Product Specifications
CAS Number
1159996-43-6
Field of Research
Pharmacology & Drug Discovery
Smiles
C (NC1=CC=C (F) C=C1) (=O) N2[C@@H] (C=3C (CC2) =CC=CC3) C4=CC=C (C (F) (F) F) C=C4
Molecular Formula
C23H18F4N2O
Molecular Weight
414.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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