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HS-276

HS-276 is a potent and selective TAK1 inhibitor with an IC50 of 8.25 nM, also showing activity against CLK2, GCK, ULK2, and MAP4K5. This orally bioavailable compound is a valuable research tool for investigating rheumatoid arthritis mechanisms in both cellular and animal models.

Product Specifications

CAS Number

2767422-72-8

Product Name Alternative

TAK1

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.67% (May vary between batches)

Solubility

DMSO:45 mg/mL (107.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.77 mM)

Smiles

C (CC) N1C=2C (N=C1NC (=O) C3=CC (C (N) =O) =CC=C3) =CC=C (CN4CCCCC4) C2

Molecular Formula

C24H29N5O2

Molecular Weight

419.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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