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Trans-isrib A17

Trans-ISRIB A17 (ISR-IN-1) is a highly potent small molecule inhibitor of the integrated stress response (ISR), exhibiting an EC50 of 0.6 nM. It is widely used in both in vitro and in vivo research to study ISR pathway biology, cellular stress mechanisms, and potential therapeutic interventions for related diseases.

Product Specifications

CAS Number

1628478-15-8

Product Name Alternative

ISR-IN-1, trans-isrib A17

Field of Research

Immunology & Inflammation

Purity

98.17% (May vary between batches)

Solubility

DMSO:Slightly soluble

Smiles

O (CC (N[C@H]1CC[C@H] (NC (COC2=CC (F) =C (Cl) C=C2) =O) CC1) =O) C3=CC (F) =C (Cl) C=C3

Molecular Formula

C22H22Cl2F2N2O4

Molecular Weight

487.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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