GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors[1].
Product Specifications
UNSPSC
12171500
Target
Carbonic Anhydrase; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gz22-4.html
Smiles
O=S(CCCC[N+]1=C(/C=C/C(CCC/2)=C(OC3=CC=C(CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCS(C4=C(NC5CCCCCCC5)C(F)=C(S(N)(=O)=O)C(F)=C4F)(=O)=O)=O)=O)C=C3)C2=C\C=C6C(C)(C)C(C=CC=C7)=C7N\6CCCCS([O-])(=O)=O)C(C)(C)C8=C1C=CC=C8)(O[Na])=O
Molecular Formula
C88H126F3N6NaO24S4
Molecular Weight
1860.21
References & Citations
[1]Žvinys G, et al. High-Affinity NIR-Fluorescent Inhibitors for Tumor Imaging via Carbonic Anhydrase IX. Bioconjug Chem. 2024 May 15.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
CA II; CA I; CA IX; CA XII
Frequently Asked Questions
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