TNNC1 Polyclonal Antibody
Product Specifications
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
Abbreviation
TNNC1
UniProt
P63316
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Full length fusion protein
Target
Tnnc1a; Cardiac troponin C; slow skeletal and cardiac muscles; TN-C; TNC; Tnnc1; TNNC1; TNNI3; Troponin C; Troponin C slow; Troponin C1 slow
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:10-1:50
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
Refer to figures
Citation 01
https://link.springer.com/article/10.1007/s11356-022-24656-4
Isotype
IgG
Available Sizes
Curated Selection
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