Tovinontrine
Tovinontrine (IMR-687) is a highly selective phosphodiesterase-9 (PDE9) inhibitor with reported IC50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively. It is a research compound investigated for sickle cell disease, with studies exploring its effects on fetal hemoglobin induction in both cellular and animal models.
Product Specifications
CAS Number
2062661-53-2
Product Name Alternative
PDE9A, IMR 687, IMR687, IMR-687, Tovinontrine
Field of Research
Metabolism Research
Purity
98.14% (May vary between batches)
Solubility
DMSO:90 mg/mL (228.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.37 mM)
Smiles
C[C@@H]1CN (Cc2ncccn2) C[C@H]1c1cn2c (ncc2c (=O) [nH]1) C1CCOCC1
Molecular Formula
C21H26N6O2
Molecular Weight
394.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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