Recombinant CSNK2A1 Monoclonal Antibody
Product Specifications
Background
Casein kinase II subunit alpha (CSNK2A1) is a catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. CSNK2A1 regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. During mitosis, CSNK2A1 functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage.
Abbreviation
CSNK2A1
UniProt
P68400
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant human CSNK2A1 fragment
Target
CK2A; casein kinase 2 alpha; Cka; CK2A1; CKII; CSNK2A3; OCNDS; CKII alpha; CSNK2A1; Cka1; Cka2; casein kinase 2 alpha 1; casein kinase 2 alpha 1; CK2A1; Cka1; Cka2; CKII; CSNK2A3; OCNDS; Casein kinase 2 alpha 1 polypeptide; Casein kinase II alpha 1; Casein kinase II alpha 1 subunit; Casein kinase II alpha subunit; Casein kinase II subunit alpha; CK II; CK II alpha; CK2 alpha; CK2 catalytic subunit alpha; CKIIalpha; CSK21; Csnk2a1-rs4
Clonality
Monoclonal,Recombinant
Clone
A462
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cell Biology; Signal Transduction
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100; IF 1:100-1:200
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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