Recombinant CSNK2A1 Monoclonal Antibody

Casein kinase II subunit alpha (CSNK2A1) is a catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. CSNK2A1 regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. During mitosis, CSNK2A1 functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage.

CK2A; casein kinase 2 alpha; Cka; CK2A1; CKII; CSNK2A3; OCNDS; CKII alpha; CSNK2A1; Cka1; Cka2; casein kinase 2 alpha 1; casein kinase 2 alpha 1; CK2A1; Cka1; Cka2; CKII; CSNK2A3; OCNDS; Casein kinase 2 alpha 1 polypeptide; Casein kinase II alpha 1; Casein kinase II alpha 1 subunit; Casein kinase II alpha subunit; Casein kinase II subunit alpha; CK II; CK II alpha; CK2 alpha; CK2 catalytic subunit alpha; CKIIalpha; CSK21; Csnk2a1-rs4