SKLB-197
SKLB-197 is a highly selective ATR inhibitor (IC50: 0.013 μM) with minimal activity against 402 other kinases. It demonstrates potent antitumor efficacy in both in vitro and in vivo models, particularly against ATM-deficient tumors, making it a valuable tool for oncology research targeting DNA damage response pathways.
Product Specifications
CAS Number
2713577-16-1
Field of Research
Molecular Biology, Signal Transduction
Purity
99.53% (May vary between batches)
Smiles
C[C@H]1N (C=2C3=C (N=C (N2) C4=C5C (NC=C5) =CC=C4) C=CC (=C3) C=6N (C) N=CC6) CCOC1
Molecular Formula
C25H24N6O
Molecular Weight
424.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Alpha-Synuclein Recombinant Rabbit Monoclonal Antibody [PSH08-83]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81415/imageurl/ha723035.webp)
HA723035 100 µL
Alpha-Synuclein Recombinant Rabbit Monoclonal Antibody [PSH08-83]
Sign In for Pricing
View Details 
GTR10405557 96 Well
Chicken ATP binding cassette sub family A member 10 (ABCA10) ELISA kit
Sign In for Pricing
View Details 
44365064 1.0 µg DNA
SLIT2 Lentiviral Vector (Mouse) (pLenti-GIII-CMV )
Sign In for Pricing
View Details