IDO1-IN-13
IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor, demonstrating an IC50 of 61.6 nM and an EC50 of 30 nM in HeLa cells. In vivo, it significantly reduced the kynurenine/tryptophan ratio by 51% in SK-OV-3 xenograft models, supporting its utility in cancer immunology and immunotherapy research.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C20H16BrN5O2S
Molecular Weight
470.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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