Mahanine
Mahanine is a natural alkaloid that induces apoptosis in leukemia U937 cells via mitochondrial membrane permeabilization and caspase-3 activation. It also acts as an epigenetic modulator in prostate cancer by inhibiting DNMT activity, leading to RASSF1A reactivation and cyclin D1 downregulation, highlighting its potential for cancer research.
Product Specifications
CAS Number
28360-49-8
Field of Research
Infectious Disease & Virology
Smiles
CC (C) =CCC[C@@]1 (C) Oc2c (C) cc3c ([nH]c4cc (O) ccc34) c2C=C1 |wU:6.6, wD:6.5, c:27, (12.99, -4.96, ;11.75, -4.04, ;10.34, -4.65, ;11.93, -2.51, ;10.7, -1.59, ;10.88, -.06, ;9.65, .86, ;10.77,1.91, ;8.8,2.15, ;7.26,2.06, ;6.42,3.35, ;7.11,4.72, ;4.88,3.26, ;4.19,1.88, ;5.03, .59, ;4.07, -.61, ;2.63, -.06, ;1.26, -.77, ; -.04, .06, ; -1.4, -.64, ; .04,1.6, ;1.41,2.31, ;2.7,1.48, ;6.57, .68, ;7.42, -.61, ;8.95, -.52, ) |
Molecular Formula
C23H25NO2
Molecular Weight
347.458
Storage Conditions
-20°C
Notes
For research use only.
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