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AKT1-IN-10

AKT1-IN-10 (Compound I-118) is a non-covalent allosteric AKT1 inhibitor with an IC50 of [1].

Product Specifications

CAS Number

[3077847-90-3]

UNSPSC

12352005

Target

Akt

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

CC1=C(C=CC(NC([C@@H]2CC[C@H](CC2)C(O)=O)=O)=N1)N3C4=NC(C5=CC=CC=C5)=CC=C4N=C3C6=C(N=CC=C6)N

Molecular Formula

C31H29N7O3

Molecular Weight

547.61

References & Citations

[1]Maria Jesus Blanco-Pillado, et, al, Substituted aminopyridine compounds for use as akt1 inhibitors, WO2025059577A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Akt1

Curated Selection

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