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Y-27632 dihydrochloride

Y-27632 dihydrochloride is a potent, cell-permeable inhibitor targeting ROCK-I and ROCK-II kinases. It is widely used in vitro to study cytoskeletal dynamics and cell adhesion, and in vivo to investigate pathways in neuroprotection, cardiovascular function, and stem cell survival.

Product Specifications

CAS Number

129830-38-2

Product Name Alternative

Epithelial-mesenchymal, hIPSCs, Inhibitor, inhibit, lineage, mesendodermal, orally, pluripotent, modulation, Apoptosis, ATP-competitive, active, cells, Y27632, Y-27632, Y-27632 2HCl, Y27632 Dihydrochloride, Y27632 dihydrochloride, Y-27632 Dihydrochloride, Y 27632, Y 27632 Dihydrochloride, Y 27632 dihydrochloride, Rho-kinase, ROCK1 (p160ROCK), ROCK2, ROCK, ROK, Rho-associated protein kinase, Rho-associated kinase, transition-like, stem

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.96% (May vary between batches)

Solubility

H2O:32.03 mg/mL (100.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.61 mM) ; DMSO:255 mg/mL (796.23 mM)

Smiles

Cl.Cl.C[C@@H] (N) [C@H]1CC[C@@H] (CC1) C (=O) Nc1ccncc1

Molecular Formula

C14H21N3O·2HCl

Molecular Weight

320.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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