WR-99210
WR99210 hydrochloride is a subnanomolar inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), effective against wild-type and multidrug-resistant mutant strains. This compound is a critical research tool for studying antimalarial drug resistance mechanisms and for conducting both in vitro enzyme assays and in vivo efficacy studies in malaria models.
Product Specifications
CAS Number
30711-93-4
Product Name Alternative
PfDHFR, WR 99210, WR99210, WR99210 hydrochloride (47326-86-3 free base), 6,6-Dimethyl-1-[3- (2,4,5-trichlorophenoxy) propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Purity
97.77% (May vary between batches)
Solubility
DMSO:55 mg/mL (127.57 mM)
Smiles
NC1=NC (N) =NC (C) (C) N1OCCCOC2=CC (Cl) =C (Cl) C=C2Cl.[H]Cl
Molecular Formula
C14H19Cl4N5O2
Molecular Weight
431.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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