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4E1rcat

4E1RCat is a small molecule dual inhibitor that disrupts the eIF4E interactions with both eIF4G and 4E-BP1, exhibiting an IC50 of 3.2 μM against eIF4G binding. It serves as a valuable research tool for studying cap-dependent translation initiation in cancer and cellular proliferation assays, both in vitro and in vivo.

Product Specifications

CAS Number

328998-25-0

Product Name Alternative

Autophagy, 4E1rcat, 4E-1rcat, Inhibitor, inhibit, eIF-4E, Eukaryotic Initiation Factor (eIF)

Field of Research

Cell Biology

Purity

98.57% (May vary between batches)

Solubility

DMSO:23.9 mg/mL (49.95 mM)

Smiles

OC (=O) c1ccc (cc1) N1C (=O) \C (=C\c2ccc (o2) -c2ccc (cc2) [N+] ([O-]) =O) C=C1c1ccccc1

Molecular Formula

C28H18N2O6

Molecular Weight

478.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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