RGFP966
RGFP966 is a potent and selective HDAC3 inhibitor with an IC50 of 0.08 μM. It is widely used in research to investigate epigenetic mechanisms in neuroscience, oncology, and metabolic studies, with applications in both cellular and animal models.
Product Specifications
CAS Number
1357389-11-7
Product Name Alternative
RGFP 966, RGFP966, RGFP-966, Inhibitor, HDAC3, HDAC, Histone deacetylases, inhibit
Field of Research
Epigenetics & Chromatin, Neuroscience
Purity
>98%
Bioactivity
Selective HDAC3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
Nc1cc (F) ccc1NC (=O) \C=C\c1cnn (C\C=C\c2ccccc2) c1
Molecular Formula
C21H19FN4O
Molecular Weight
362.40
References & Citations
Rudy Matheson 1 & Kohei Chida 2 & Hui Lu 1,3 & Victoria Clendaniel 1 & Marc Fisher 4 & Ajith Thomas 5 & Eng H. Lo 6 & Magdy Selim 4 & Amjad Shehadah 4 Neuroprotective Effects of Selective Inhibition of Histone Deacetylase 3 in Experimental Stroke Ponatinib inhibitor, (2024)
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2E) -N- (2-Amino-4-fluorophenyl) -3-[ (2E) -1- (3-phenyl-2-propen-1-yl) -1H-pyrazol-4-yl]-2-propenamide
Available Sizes
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