AM095 free acid
AM095 (free acid) is a potent and selective antagonist of the LPA1 receptor, demonstrating sub-micromolar IC50 values against both human and mouse recombinant proteins. This small molecule inhibitor is a valuable research tool for investigating LPA1-mediated pathways in fibrosis, neuropathic pain, and cancer metastasis, as evidenced by its use in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1228690-36-5
Product Name Alternative
AM095, AM-095, AM095 free acid, AM-095 free acid, AM 095, human LPA1, Inhibitor, mouse LPA1, inhibit, LPA1, LPA Receptor, LPAReceptor, LPLReceptor, LPL, LPL Receptor, Lysophospholipid Receptor
Field of Research
Pharmacology & Drug Discovery
Purity
99.88% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (5.48 mM) ; DMSO:67.3 mg/mL (147.43 mM)
Smiles
C[C@@H] (OC (=O) Nc1c (C) noc1-c1ccc (cc1) -c1ccc (CC (O) =O) cc1) c1ccccc1
Molecular Formula
C27H24N2O5
Molecular Weight
456.49
Storage Conditions
-20°C
Notes
For research use only.
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