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COH34

COH34 is a potent and selective PARG inhibitor (IC50 0.37 nM) that acts by stabilizing PAR chains at DNA damage sites, thereby trapping DNA repair factors. This mechanism makes it a valuable chemical probe for studying DNA repair pathways in both cellular and biochemical assays.

Product Specifications

CAS Number

906439-72-3

Product Name Alternative

PARG, COH 34, COH34, COH-34, 1-[ (E) - (4-methylphenyl) sulfanyliminomethyl]naphthalen-2-ol

Field of Research

Cell Biology

Purity

98.21% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.41 mM) ; DMSO:15 mg/mL (51.13 mM)

Smiles

Cc1ccc (S\N=C\c2c (O) ccc3ccccc23) cc1

Molecular Formula

C18H15NOS

Molecular Weight

293.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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